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Symbol Name ID |
Sf3b1
splicing factor 3b, subunit 1 MGI:1932339 |
| Darker colors indicate more annotations |
| Human Phenotypes | Myelodysplasia |
| Disease(s) Associated with SF3B1 | |
| myelodysplastic syndrome |
| Mouse Phenotypes | abnormal erythropoiesis |
abnormal myelopoiesis |
extramedullary hematopoiesis |
hypochromic macrocytic anemia |
macrocytic anemia |
impaired hematopoiesis |
abnormal bone marrow cell morphology/development |
decreased granulocyte monocyte progenitor cell number |
abnormal erythroid progenitor cell morphology |
decreased erythrocyte cell number |
decreased hemoglobin content |
increased mean corpuscular volume |
macrocytosis |
thrombocytosis |
increased hematopoietic stem cell number |
increased spleen red pulp amount |
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| Availability | Mouse Genotype | ||||||||||||||||
| Sf3b1tm1Hko/Sf3b1+ | |||||||||||||||||
| Sf3b1tm1.1Mdf/Sf3b1+ Tg(Mx1-cre)1Cgn/? (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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